Computed tomography brain changes in Parkinsonian dementia
Identifieur interne : 002929 ( Main/Exploration ); précédent : 002928; suivant : 002930Computed tomography brain changes in Parkinsonian dementia
Auteurs : R. Inzelberg [Israël] ; T. Treves [Israël] ; I. Reider [Israël] ; I. Gerlenter [Israël] ; D. Korczyn [Israël]Source :
- Neuroradiology [ 0028-3940 ] ; 1987-11-01.
Abstract
Summary: In order to evaluate the relationship between brain atrophy and the motor and cognitive function in Parkinson's disease, we have evaluated CT changes in 132 consecutive patients and compared them to measures of physical and mental decline, using intercorrelations and variance analysis. The result demonstrated age as a most important factor relating to brain atrophy. After correction for this determinant, it became clear that the motor and cognitive parameters were interdependent but they affected similar CT parameters. The effect of motor decline was the stronger of the two and it was the only one which correlated with cortical atrophy. The results support the notion of subcortical changes underlying the dementia of Parkinson's disease.
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DOI: 10.1007/BF00350436
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Inzelberg</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv</wicri:regionArea><wicri:noRegion>Ramat Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Treves, T" sort="Treves, T" uniqKey="Treves T" first="T." last="Treves">T. Treves</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv</wicri:regionArea><wicri:noRegion>Ramat Aviv</wicri:noRegion></affiliation></author><author><name sortKey="Reider, I" sort="Reider, I" uniqKey="Reider I" first="I." last="Reider">I. 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Korczyn</name><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv</wicri:regionArea><wicri:noRegion>Ramat Aviv</wicri:noRegion></affiliation><affiliation wicri:level="1"><country xml:lang="fr">Israël</country><wicri:regionArea>Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv</wicri:regionArea><wicri:noRegion>Ramat Aviv</wicri:noRegion></affiliation></author></analytic><monogr></monogr><series><title level="j">Neuroradiology</title><title level="j" type="sub">A Journal Devoted to Neuroimaging and Interventional Neuroradiology</title><title level="j" type="abbrev">Neuroradiology</title><idno type="ISSN">0028-3940</idno><idno type="eISSN">1432-1920</idno><imprint><publisher>Springer-Verlag</publisher><pubPlace>Berlin/Heidelberg</pubPlace><date type="published" when="1987-11-01">1987-11-01</date><biblScope unit="volume">29</biblScope><biblScope unit="issue">6</biblScope><biblScope unit="page" from="535">535</biblScope><biblScope unit="page" to="539">539</biblScope></imprint><idno type="ISSN">0028-3940</idno></series><idno type="istex">49022078CFEA4B9D530D35854364F9E34EA4A450</idno><idno type="DOI">10.1007/BF00350436</idno><idno type="ArticleID">Art9</idno><idno type="ArticleID">BF00350436</idno></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0028-3940</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass><langUsage><language ident="en">en</language></langUsage></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Summary: In order to evaluate the relationship between brain atrophy and the motor and cognitive function in Parkinson's disease, we have evaluated CT changes in 132 consecutive patients and compared them to measures of physical and mental decline, using intercorrelations and variance analysis. The result demonstrated age as a most important factor relating to brain atrophy. After correction for this determinant, it became clear that the motor and cognitive parameters were interdependent but they affected similar CT parameters. The effect of motor decline was the stronger of the two and it was the only one which correlated with cortical atrophy. The results support the notion of subcortical changes underlying the dementia of Parkinson's disease.</div></front></TEI><affiliations><list><country><li>Israël</li></country></list><tree><country name="Israël"><noRegion><name sortKey="Inzelberg, R" sort="Inzelberg, R" uniqKey="Inzelberg R" first="R." last="Inzelberg">R. Inzelberg</name></noRegion><name sortKey="Gerlenter, I" sort="Gerlenter, I" uniqKey="Gerlenter I" first="I." last="Gerlenter">I. Gerlenter</name><name sortKey="Korczyn, D" sort="Korczyn, D" uniqKey="Korczyn D" first="D." last="Korczyn">D. 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